Skip to main content

Table 3 Skin abnormalities in XP-CS

From: Xeroderma pigmentosum-Cockayne syndrome complex

Skin manifestations #/total (percent)
Photosensitivity (laboratory measured)a 40/40 (100)
Sunburns easily 32/33 (97)
Solar lentigines/abnormal freckling 35/37 (95)
Very dry skin 14/15 (93)
Wizened/progeroid facial appearance 16/23 (70)
Skin cancer 5/33 (15)
  1. aTested in skin fibroblasts as abnormalities after UV irradiation (survival, DNA repair, recovery of RNA synthesis, or unscheduled DNA synthesis)