Prevalence of treated disorder (per 100,000) | p-value | |||
---|---|---|---|---|
<50 to >10 | ≤10 to >1 | ≤1 | ||
n = 19 | n = 23 | n = 13 | ||
Median assessment time (range) | 203 (164–251) | 195 (126–392) | 232 (153–439) | 0.409 |
Median daily cost (range)a | $55 ($13–$252) | $186 ($26–$1800) | $796 ($181–$1460) | 0.0001 |
Median number of RCTs (range) | 2 (1–6) | 2 (1–4) | 1 (0–4) | 0.100 |
Median number of patients in RCTs (range) | 120 (15–555) | 118 (12–742) | 58 (11–177) | 0.020 |
No. with a negative recommendation | 5 (26.3%) | 10 (43.5%) | 10 (76.9%) | 0.006 |
No. with acceptable clinical efficacy evidence | 14 (73.7%) | 11 (47.8%) | 2 (15.4%) | 0.001 |
No. with concern about cost-effectiveness analysis | 9 (47.4%) | 18 (78.3%) | 12 (92.3%) | 0.004 |
No. with high cost or need for price reduction stated in the recommendation | 3 (15.8%) | 10 (43.5%) | 6 (46.2%) | 0.057 |
No. with high cost noted elsewhere in the report | 0 (0.0%) | 1 (4.3%) | 2 (15.4%) | 0.067 |
No. with high cost or need for price reduction noted anywhere in the report | 3 (15.8%) | 11 (47.8%) | 8 (61.5%) | 0.007 |