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Table 4 Determination of inadequate response to colchicine (resistance)

From: A survey of resistance to colchicine treatment for French patients with familial Mediterranean fever

Symptoms

Population

n (%)

Group Ia

n (%)

Group IIb

n (%)

p value ¥

Frequency of attacks

    

  > 6/year

42%

23%

65%

< 0.08

  > 4/6 months

26%

30%

22%

ns

Biological inflammation

45%

47%

44%

ns

Intolerance to treatment

19%

16%

22%

ns

Amyloidosis

 

22%

0%

0.02

Renal failure

 

20%

0%

0.02

Other reasons

23 %

18%

26%

ns

  1. ¥By chi-square test
  2. *Group I: Adult care setting
  3. **Group II: Pediatric care setting