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Table 4 Determination of inadequate response to colchicine (resistance)

From: A survey of resistance to colchicine treatment for French patients with familial Mediterranean fever

Symptoms Population
n (%)
Group Ia
n (%)
Group IIb
n (%)
p value ¥
Frequency of attacks     
  > 6/year 42% 23% 65% < 0.08
  > 4/6 months 26% 30% 22% ns
Biological inflammation 45% 47% 44% ns
Intolerance to treatment 19% 16% 22% ns
Amyloidosis   22% 0% 0.02
Renal failure   20% 0% 0.02
Other reasons 23 % 18% 26% ns
  1. ¥By chi-square test
  2. *Group I: Adult care setting
  3. **Group II: Pediatric care setting