Fig. 2From: Efficacy, safety and population pharmacokinetics of sapropterin in PKU patients <4 years: results from the SPARK open-label, multicentre, randomized phase IIIb trial a Adjusted mean dietary Phe tolerance (mg/kg/day) a and mean Phe change from baseline (μmol/L) b Error bars represent 95% confidence intervals. Phe, phenylalanine. CI, confidence interval; Phe, phenylalanineBack to article page