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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Does the low prevalence affect the sample size of interventional clinical trials of rare diseases? An analysis of data from the aggregate analysis of clinicaltrials.gov

Fig. 1

Jittered boxplot of (a) phase 2 and (b) phase 3 trials with either actual (brown triangle) or anticipated (blue dot) sample size by prevalence class. Each symbol represents one observation and the mean sample size is indicated by the red diamond. Number of trials contributing to the plot is given at the top row, median sample size in the second row, first quartile in the third row and third quartile in the last row of the bottom of each boxplot

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