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Table 2 Published prospective and retrospective studies assessing the prevalence of non-optic gliomas in NF1

From: Non-optic glioma in adults and children with neurofibromatosis 1

Authors Study type Cohort size Age range of cohorts (in years) Median age at diagnosis Number of tumour patients Rates of tumours How were tumour patients identified?
Cnossen et al. [16] P 150 0–18 Unknown 4 2.70% Symptomatic patients
Zöller et al. [17] P 70 20–81 Unknown 1 1.43% Cross-referencing with cancer registry
Friedman and Birch [11] R 684 0–73 <6 years 25 3.65% MRI/CT*
McGaughran et al. [18] R 523 0–74 Unknown 12 2.29% Symptomatic patients
Menor et al. [19] R 72 0.8–14 Unknown 8 11% MRI*
Seminog and Goldacre [20] R 6739 0–80+ Unknown 322 4.78% Hospital records
Varan et al. [21] R 473 0–33 8 years 11 2.32% Symptomatic patients
  1. *denotes studies for which convenience MRI/CT images were used