Table 2 Published prospective and retrospective studies assessing the prevalence of non-optic gliomas in NF1
From: Non-optic glioma in adults and children with neurofibromatosis 1
Authors | Study type | Cohort size | Age range of cohorts (in years) | Median age at diagnosis | Number of tumour patients | Rates of tumours | How were tumour patients identified? |
|---|---|---|---|---|---|---|---|
Cnossen et al. [16] | P | 150 | 0–18 | Unknown | 4 | 2.70% | Symptomatic patients |
Zöller et al. [17] | P | 70 | 20–81 | Unknown | 1 | 1.43% | Cross-referencing with cancer registry |
Friedman and Birch [11] | R | 684 | 0–73 | <6 years | 25 | 3.65% | MRI/CT* |
McGaughran et al. [18] | R | 523 | 0–74 | Unknown | 12 | 2.29% | Symptomatic patients |
Menor et al. [19] | R | 72 | 0.8–14 | Unknown | 8 | 11% | MRI* |
Seminog and Goldacre [20] | R | 6739 | 0–80+ | Unknown | 322 | 4.78% | Hospital records |
Varan et al. [21] | R | 473 | 0–33 | 8 years | 11 | 2.32% | Symptomatic patients |