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Table 1 Clinical features of non-optic gliomas in NF1 patients

From: Non-optic glioma in adults and children with neurofibromatosis 1

Patient number

Sex

Age at first scan with glioma (in years)

Symptoms

Histology

Location

Status

Treatment

1

M

20.9

Headache

PA Grade 1

Frontal

Decreased size

Surgery

2

F

41.6

No

 

Temporal

Decreased size

Chemotherapy (breast cancer)

3

F

48.6

No

 

Brainstem

Stable

 

4

F

50.8

No

 

Temporal

No follow up

 

5

F

23.4

Seizures

 

Brainstem

Stable

 

6

F

10.0

Seizures, headache

 

Cerebellum

Stable

 

7

M

31.3

No

 

Brainstem

Stable

 

8

M

13.1

No

 

Frontal

Stable

 

9ab

M

44.6

Ataxia

 

Cerebellum

Stable

 

9bb

M

44.6

Ataxia

 

Cerebellum

Stable

 

9cab

M

50.5

Ataxia

PA Grade 1

Cerebellum

Increased, then decreased size

Surgery

10

M

6.5

No

PA Grade 1

Brainstem

Increased size & enhancement

Chemotherapy, biopsy

11ab

F

34.9

No

 

Brainstem

No follow up

 

12a

F

16.4

No

PA Grade 1

Corpus Callosum

Increased enhancement

Incomplete resection before study begin

12ba

F

25.3

No

 

Brainstem

Stable

 

13

F

38.5

No

 

Cerebellum

Stable

 

14

M

17.2

Seizures, headache

PA Grade 1

Cerebellum

Stable

Surgery

15

M

21.3

No

PA Grade 1

Corpus Callosum

Decreased size & enhancement

Surgery

16

M

42.5

No

 

Temporal

Stable

 

17

M

42.7

Seizures

DNET

Cerebellum

Stable

Incomplete resection before study begin

18a

F

14.8

No

PA Grade 1

Corpus Callosum

No follow up

Surgery

18b

F

14.8

No

 

Thalamus

No follow up

 

19ab

F

18.3

No

 

Brainstem

Increased in size

 

20

F

16.0

No

 

Internal capsule

Decreased enhancement

 

21

F

39.8

No

 

Cerebellum

Stable

 

22a

F

10.9

No

 

Cerebellum

Decreased enhancement

 

22b

F

10.9

No

 

Cerebellum

Increased, then decreased in size

 

22c

F

10.9

No

 

Cerebellum

Stable

 

23

M

17.4

No

 

Brainstem

Increased size & enhancement

 

24a

M

18.1

Double vision, nystagmus

PA Grade 1

Brainstem

Decreased size

Surgery

24b

M

18.1

Double vision, nystagmus

 

Corpus Callosum

Increased size

 

24c

M

18.1

Double vision, nystagmus

 

Cerebellum

Stable

 
  1. Abbreviations: PA pilocytic astrocytoma, M male, F female, DNET dysembryoplastic neuroepithelial tumour
  2. adenotes patients with newly-appearing tumours
  3. bdenotes patients with concurrent optic gliomas