Table 1 Demographic, clinical, respiratory and sleep variables in patients with congenital central hypoventilation syndrome (CCHS) and healthy controls
Patients with CCHS | Healthy Controls | P value | |
|---|---|---|---|
Number | 14 | 15 | |
Gender, F/M | 9/5 | 11/4 | 0.70 |
Age, y | 23.0 (19.0; 24.8) | 23.0 (22.0; 26.0) | 0.42 |
Body mass index, kg/m2 | 21.7 (20.7; 24.0) | 21.7 (20.1; 22.8) | 0.95 |
Epworth sleepiness score, 0-24 | 7 (2; 8) | 6 (4; 7) | 0.73 |
NIV/Tracheotomy | 10/4 | NA | NA |
Blood gases | |||
pH | 7.42 (7.38; 7.44) | NA | NA |
PaCO2, mmHg | 40 (34; 44) | NA | NA |
PaO2, mmHg | 101 (86: 112) | NA | NA |
Awake SpO2, % | 98 (96; 99) | NA | NA |
Total sleep period, min | 514.5 (489.5; 585.8) | 552.0 (522.5; 588.5) | 0.47 |
Total sleep time, min | 484.0 (432.8; 512.3) | 500.0 (446.5; 540.0) | 0.42 |
Sleep efficiency, % | 93.7 (82.9; 95.1) | 92.9 (88.6; 95.0) | 0.86 |
Latency to, min | |||
Sleep onset | 14.0 (7.0; 20.5) | 33.0 (18.0; 49.0) | 0.052 |
N3 | 26.3 (24.0; 30.1) | 49.5 (34.3; 66.9) | 0.005 |
REM sleep | 64.5 (52.3; 81.5) | 64.0 (56.5; 69.0) | 0.95 |
Sleep stages, min | |||
N1 | 17.5 (10.5; 25.5) | 26.0 (15.5; 32.0) | 0.21 |
N2 | 209.5 (187.3; 247.0) | 223.0 (190.0; 245.5) | 0.65 |
N3 | 117.0 (109.8; 133.8) | 120.0 (106.0; 142.0) | 0.83 |
REM sleep | 110.0 (90.3; 122.3) | 126.0 (109.0; 133.0) | 0.11 |
Arousals (/h) | 13.3 (8.5; 17.4) | 11.5 (9.2; 15.2) | 0.79 |
Periodic leg movements (/h) | 0.1 (0.0; 3.3) | 0.2 (0.0; 0.7) | 0.95 |