Table 1 Demographic, Disease, and Treatment Characteristics of Study Participants
From: The burden of amyloid light chain amyloidosis on health-related quality of life
Baseline sample | ||
|---|---|---|
N = 341 | ||
n | % | |
Mean age, years (SD) | 60.6 (10.2) | |
Range, years (median) | 23–85 (61) | |
Gender (n = 340)a | ||
Male | 160 | 47.1 |
Female | 180 | 52.9 |
Race/ethnicity | ||
White | 304 | 89.1 |
Other | 37 | 10.9 |
Education (n = 322)a | ||
≤ High school diploma or GED® | 26 | 8.1 |
Some college but no degree | 50 | 15.5 |
A Associate’s degree or technical certificate | 49 | 15.2 |
Bachelor’s degree | 109 | 33.9 |
Graduate degree | 88 | 27.3 |
Marital status (n = 330)a | ||
Married | 271 | 82.1 |
Other | 59 | 17.9 |
Employment status | ||
Currently employed for pay | 115 | 38.3 |
US region of residence | ||
Northeast | 68 | 19.9 |
Southeast | 56 | 16.4 |
Midwest | 54 | 15.8 |
Southwest | 24 | 7.0 |
West | 81 | 23.8 |
Other/unknown | 58 | 17.0 |
Mean time since diagnosis, years (SD) | 4.5 (4.0) | |
Range (median) | 1 month–28 years (3.5 years) | |
Time between onset of symptoms and diagnosis | ||
Less than 6 months | 96 | 28.2 |
Between 6 months and 1 year | 97 | 28.4 |
Between 1 and 2 years | 76 | 22.3 |
Between 2 and 3 years | 31 | 9.1 |
More than 3 years | 41 | 12.0 |
Number of doctors seen before diagnosis | ||
One | 11 | 3.2 |
Two | 57 | 16.7 |
Three | 60 | 17.6 |
Four | 68 | 19.9 |
Five or more | 145 | 42.9 |
Organs/systems impactedb | ||
Heart (cardiac) | 178 | 52.2 |
Kidney | 214 | 62.8 |
Liver | 49 | 14.4 |
Nervous system | 126 | 37.0 |
Gastrointestinal | 148 | 43.4 |
Other | 117 | 34.3 |
Number of organs involved | ||
One | 95 | 27.9 |
Two | 89 | 26.1 |
Three or more | 157 | 46.0 |
History of multiple myeloma | 71 | 22.8 |
No. treatment series received | ||
None | 20 | 5.9 |
One | 70 | 20.5 |
Two | 76 | 22.3 |
Three | 61 | 17.9 |
Four | 25 | 7.3 |
Five or more | 89 | 26.1 |
Ever underwent stem cell transplantation | 180 | 52.9 |
Most recent hematologic response status (n = 321)c | ||
No response to treatment | 20 | 6.2 |
Partial hematologic response or partial remission | 126 | 39.3 |
Complete hematologic response or complete remission | 140 | 43.6 |
I do not know | 35 | 10.9 |