Skip to main content

Table 3 Multivariate analysis for PCS and MCS of the SF-12v2 and coefficients#1

From: Impacts of caring for a child with the CDKL5 disorder on parental wellbeing and family quality of life

Measure

 

PCS

MCS

 

Coefficient (95% CI)

Coefficient (95% CI)

Feeding pattern

Oral intake only

Reference

Reference

Combination use

−1.01 (−5.63, 3.60)

−1.49 (−8.36, 5.37)

Enteral nutrition only

−4.51** (−8.12, −0.89)

6.67** (1.29 to 12.05)

Dietary concerns

None

Reference

Reference

Occasional

−4.98** (−8.11, −1.86)

−0.88 (−5.97, 4.20)

Frequent or constant

−1.81 (−5.51, 1.88)

0.30 (−5.72, 6.32)

Floor sitting

No assistance

Reference

Reference

Some assistance

0.21 (−4.01, 4.42)

−1.59 (−8.14, 4.96)

Maximal assistance/unable

−2.27 (−5.44, 0.90)

1.03 (−3.89, 5.96)

Taking 10 steps forward

No assistance

Reference

Reference

Some assistance

1.20 (−3.52, 5.91)

−1.23 (−8.59, 6.14)

Maximal assistance/unable

−1.85 (−5.34, 1.64)

0.15 (−5.30, 5.61)

Eye contact

No

Reference

Reference

Yes

1.04 (−1.67, 3.75)

1.77 (−2.46, 6.00)

Communication

No/Simple method

Reference

Reference

Complex gestures/vocalisation

0.45 (−2.58, 3.48)

−0.85 (−5.42, 3.72)

Sign/Spoken language

1.03 (−3.00, 5.06)

0.14 (−5.93, 6.21)

Seizure frequency

Absent

Reference

Reference

Yearly/Monthly

−0.55 (−6.78, 5.68)

−2.82 (−12.11, 6.46)

Weekly

0.42 (−5.41, 6.25)

−3.42 (−12.11, 5.27)

1 to 5 times a day

−0.76 (−5.88, 4.35)

−1.90 (−9.52, 5.73)

At least 5 times a day

−0.17 (−6.07, 5.72)

0.09 (−8.69, 8.88)

Sleep difficulties

1.00 to 1.50 (1st quartile)

Reference

Reference

1.50 to 1.81 (2nd quartile)

0.37 (−3.31, 4.04)

−2.58 (−8.11, 2.95)

1.81 to 2.17 (3rd quartile)

2.12 (−1.65, 5.89)

−2.57 (−8.25, 3.10)

2.17 to 5.00 (4th quartile)

1.02 (−2.88, 4.93)

−8.04** (−13.91, −2.16)

Hospitalisation rate

0 to 0.38 (1st quartile)

Reference

Reference

0.38 to 0.86 (2nd quartile)

−0.60 (−4.49, 3.30)

−1.13 (−7.01, 4.73)

0.86 to 2.14 (3rd quartile)

−2.27 (−6.42, 1.87)

−4.22 (−10.47, 2.03)

2.14 to 13.70 (4th quartile)

−1.15 (−5.31, 3.00)

−0.88 (−7.15, 5.38)

Respite care

None

Reference

Reference

Formal only

0.08 (−4.63, 4.79)

1.54 (−5.63, 8.69)

Informal only

−0.80 (−4.57, 2.97)

−1.54 (−7.26, 4.18)

Both formal and informal

1.00 (−2.79, 4.78)

−2.73 (−8.48, 3.02)

Financial difficulty

No

Reference

Reference

Yes

−1.76 (−4.43, 0.92)

−4.75** (−8.78, −0.71)

  1. #1Adjusted for parent’s age (a continuous variable), parent’s qualification (a binary variable; university degree or lower), parent’s work status, number of siblings, the first child, child’s age (a continuous variable) and child’s country of birth (a binary variable; North America or others)
  2. **p <0.05