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Table 2 Comparison of symptomatology in five patients with MS

From: Moebius sequence –a multidisciplinary clinical approach

 

No. 1

No. 2

No. 3

No. 4

No. 5

Baseline demographics

 Age (yrs)

3

7

15

18

19

 Sex (M: Male, F: Female)

M

F

F

F

F

 Height (cm)

103

137

166.5

167

160

 Weight (kg)

16.5

30.3

47.5

60

46

Mental and developmental

 Strengths and Difficulties Questionnaire (SDQ)

  Overall Stress (0–13)

8

2

3

14

13

  Emotional distress (0–2)

1

0

1

6

4

  Behavioural difficulties (0–3)

2

0

1

0

2

  Hyperactivity and concentration difficulties (0–5)

4

0

1

4

5

  Difficulties getting along with other children (0–2)

1

2

0

4

2

  Kind and helpful behavior (7–10)

8

10

7

7

9

  Impact of any difficulties on the child’s life (0)

0

0

0

4

1

 Diagnostic predictions LR: Low Risk, MR: Medium Risk

  Any disorder

LR

LR

LR

MR

LR

  Emotional disorder (anxiety, depression etc.)

LR

LR

LR

MR

LR

  Behavioural disorder

LR

LR

LR

LR

LR

  Hyperactivity or concentration disorder

LR

LR

LR

LR

LR

Obstetrics

 Conception (S:Spontaneous)

S

S

S

S

S

 Mothers parity (0:nullipara, 1:multipara)

0

0

1

0

0

 Mothers uterus

normal

normal

normal

bicornuate

unicornuate

 Gestational age (weeks)

41

40

35

39

36

 Birth weight (grams)

3240

3600

1950

3500

2135

 Fetal presentation (C:cephalic, B: breach)

C

C

C

C

B

 Delivery mode (V: vaginal, CS: caesarean section)

V

V

V

V

CS

 Apgar Score (1 & 5 min)

5/10

10/10

10/10

10/10

6/7

 Breastfeeding Established

No

Yes

No

Yes

No

Ophthalmology

 Abducens paralysis

Yes

Yes

Yes

Yes

Yes

 Facial paralysis

Yes

Yes

Yes

Yes

Yes

 Previous strabismus surgery

Yes

No

Yes

Yes

No

 Lacrimation abnormality

No

No

No

Yes

Yes

Odontology

 DMFS a

0

0

3

1

2

 Enamel hypomineralisation b

No

No

Yes

Yes

Yes

 HOB, Horizontal overbite (ref. value 3.3 (1.1) mm)

6

4

4

3

1

 VOB, Vertical overbite (ref. value 2.7 (1.2) mm)

1

5

4

−4

1

 Gingivitis, (range 0–12 index teeth)

4

0

2

5

1

 Tongue asymmetry

No

Yes

Yes

No

Yes

 NOT-S (range 0–12)

1

1

3

6

8

 MOC (ref. mean (range): 45 (25–70) mm) c

n.a.

45

44

53

39

 Smile surgery d

No

Yes

No

Yes

No

Craniofaciale

 Sagittal intermax. relationsship (ss-n-pg)

n.a.

 Maxillary prognathism (s-n-ss)

n.a.

 Incisor inclination, superior

n.a.

-

-

-

 Alveolar prognathism, superior

n.a.

-

-

-

-

 Mandibular prognathism Pg (s-n-pg)

n.a.

-

-

-

-

 Incisor inclination, inferior

n.a.

-

-

-

-

 Alveolar prognathism, inferior

n.a.

 Vertical intermax. relationship (NL/ML)

n.a.

-

-

 Maxillary inclination (NSL/NL)

n.a.

-

-

-

 Occlusal plane, superior (OLs/NL)

n.a.

-

 Mandibular inclination (NSL/ML)

n.a.

-

-

-

 Occlusal plane, inferior (OLi/ML)

n.a.

-

Orthopaedics

 Poland syndrome

No

No

No

No

No

 Scoliosis

Yes

Yes

Yes

Yes

Yes

 Syndactyly

Yes

No

Yes

No

No

 Adactyly

Yes

No

Yes

No

No

 Camptodactyly

Yes

Yes

Yes

No

No

 Bracydactyly

Yes

No

Yes

No

No

 CTEV (Club feet)

No

No

No

Yes

No

 Pes calcaneovalgus

No

No

Yes

Yes

No

 Macrodactyly

No

Yes

Yes

Yes

No

 Curly toes

Yes

No

Yes

Yes

Yes

Pedobarography

 Foot length (cm), R/L

n.a.

18.9/19.3

21.4/21.6

21/21

22.2/22.0

 Balance eyes-open Distance of Center of Force (cm)

n.a.

92.8

90.4

81.5

123.7

 Total foot force (kg), R/L

n.a.

29.9/23.57

n.a./78.8

100.7/83.2

56.1/ n.a.

 Total foot contact area (cm2) R/L

n.a.

52.39/67.1

n.a./81.2

88.3/81.6

84.4/ n.a.

 Total foot peak contact pressure (mmHg), R/L

n.a.

2493/2775

n.a./8586

8080/9470

4331/ n.a.

 Region of peak contact pressure, R/L f

n.a.

MH/M3

n.a./ M3

MH/MH

M5/ n.a.

  1. n.a Not applicable
  2. anumber of dental surfaces with decay or filling because of caries. bpresence of one or more molars with enamel-hypomineralisation. cmaximal opening capacity: interincisal distance on unassisted mouth opening + VOB. dprevious transplantation of a muscle grafted from the thigh to the corners of the mouth to improve facial expression [22, 23, 26]. eCraniofacial values compared to mean values and standard-deviation (SD) in 51 untreated healthy females with normal teeth and occlusion. Arrows indicate deviations from reference-value > 1 SD. fMH: Medial Heel Region, M3: Third Metatarsal Region, M5: Fifth Metatarsal Region