Table 1 Canavan disease patients reported with cytotoxic edema
Reference | Gender | Age (months) | Seizures | Delay | Hypotonia | Spasticity | Macrocephaly | Affected brain structures | Abnormal DWI brain structures |
|---|---|---|---|---|---|---|---|---|---|
a | m | 17 | na | na | na | na | na | sc | sc |
b | m | 15 | + | + | – | + | + | bs, cer, p, t, gp | bs, cer, p, t, gp |
c | m | 72 | na | na | na | na | na | sc, cc | sc, cc |
c | m | 12 | na | na | na | na | na | sc, ppv | sc |
d | m | 11 | + | + | – | – | + | sc, bs | sc, bs |
e | m | 10 | – | + | + | – | + | sc, gp, t | sc, gp, t |
f | na | 17 | + | + | – | + | – | sc, gp, t, cer | sc, gp, t, cer |
f | na | 171 | – | + | – | + | microcephaly | sc | sc |
g | m | 0.8 | na | na | na | na | + | sc, bs, t, cer, bg | sc, bs, t, bg |
h | m | 7 | na | na | na | na | na | sc | sc |
i | f | 84 | – | + | – | – | – | bg, sc | bg, sc |
j | m | 4 | + | – | – | – | – | bg, sc | bg, sc |
k | m | 2 | – | – | – | – | – | bs, sc, intcap | bs, sc, intcap |