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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Cytotoxic edema and diffusion restriction as an early pathoradiologic marker in canavan disease: case report and review of the literature

Fig. 1

a-h Axial MRIs. a DWI shows hyperintensity in the internal capsule and subcortical white matter; B) ADC demonstrates corresponding hypointensities; c T2 FLAIR image; d T1 image. e DWI with hyperintensities in the subcortical white matter; f Corresponding ADC hypointensities; g T2 image; d T1 image. i Single voxel MRS demonstrates increased NAA (arrow, peak at 2.02 ppm; choline, asterisk, 3.2 ppm; creatine, arrowhead, 3 ppm); inset shows area of analysis in the posterior left hemisphere

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