Fig. 1From: Cytotoxic edema and diffusion restriction as an early pathoradiologic marker in canavan disease: case report and review of the literature a-h Axial MRIs. a DWI shows hyperintensity in the internal capsule and subcortical white matter; B) ADC demonstrates corresponding hypointensities; c T2 FLAIR image; d T1 image. e DWI with hyperintensities in the subcortical white matter; f Corresponding ADC hypointensities; g T2 image; d T1 image. i Single voxel MRS demonstrates increased NAA (arrow, peak at 2.02Â ppm; choline, asterisk, 3.2Â ppm; creatine, arrowhead, 3Â ppm); inset shows area of analysis in the posterior left hemisphereBack to article page