Table 1 Regulation of MECP2 expression by transcription factors and microRNA

Transcription factors targeting MECP2 cis-elements [27–29]

Activation by BRN3, MYT1, SP1, SP3, C/EBP, CTCF, E2F1, TAF1, TAP1

Repression by REST, BRN2, BCL6,

Trans-regulatory elements of MECP2 [30]

Activation by HNRNPF

Repression by HNRNPH1

miRNA (posttranscriptional repression) [31–35]

hsa-miR-483- 5p, hsa-miR-132-5p, hsa-miR-152-3p, hsa-miR-199a-3p, hsa-miR-30a-3p, and hsa-miR-130b-3p