Table 1 The renal parameters of the SIOD patients included in this study
From: Increased Wnt and Notch signaling: a clue to the renal disease in Schimke immuno-osseous dysplasia?
Patient ID | Age at onset (years) | Age at death (years) | Nephrotic syndrome | Hypertension | Proteinuria | Hypercholesterolemia | Renal dialysis | Age at renal dialysis (years) | Renal transplant | Age at renal transplantation (years) | Renal pathology |
|---|---|---|---|---|---|---|---|---|---|---|---|
SD4b | 3 | 8 | + | + | + | ? | − | n/a | − | n/a | FSGS |
SD26 | <4 | 8 | + | + | + | + | + | 5 | − | n/a | FSGS |
SD60 | 7 | 13.7 | + | + | + | ? | + | 12.5 | + | 13 | FSGS |
SD79 | <4 | 10 | + | − | + | − | − | n/a | − | n/a | FSGS |
SD120 | 4.5 | 5.4 | + | + | + | + | − | n/a | − | n/a | FSGS |
SD121 | 2.5 | 4.8 | + | − | + | + | − | n/a | − | n/a | Diffuse podocytopathy with early features of FSGS |
SD131 | 3 | 4.6 | + | + | + | + | + | 3.8 | − | n/a | Global glomerulosclerosis likely secondary to FSGS |
SD146 | 2 | 4 | − | − | + | + | − | n/a | − | n/a | FSGS |