TSC2 (N = 5) | TSC1 (N = 4) | No mutation (N = 1) | All patients with TSC (N = 10) | Controls (N = 10) | Expression ratio TSC/Control | P value | Benjamini-Hochberg FDR | |
---|---|---|---|---|---|---|---|---|
miR-142-5p | −1.71 ± 0.26 | −1.35 ± 0.53 | −2.49 | −1.65 ± 0.49 | −0.52 ± 0.34 | 0.46 | 0.0000 | 0.0010 |
miR-199a-5p | −2.93 ± 0.56 | −2.84 ± 0.34 | Undetected | −2.89 ± 0.47 | −1.06 ± 0.73 | 0.28 | 0.0000 | 0.0010 |
miR-142-3p | 0.84 ± 0.50 | 0.73 ± 0.23 | 1.06 | 0.82 ± 0.38 | 1.78 ± 0.57 | 0.52 | 0.0003 | 0.0146 |
miR-136-5p | −3.88 ± 0.85 | −4.29 ± 0.51 | −3.44 | −3.98 ± 0.69 | −2.35 ± 0.77 | 0.32 | 0.0005 | 0.0156 |
miR-130a-3p | −0.71 ± 0.33 | −0.57 ± 0.18 | −1.88 | −0.77 ± 0.46 | −1.70 ± 0.53 | 1.90 | 0.0006 | 0.0156 |
miR-378a-3p | −0.57 ± 0.33 | −0.87 ± 0.40 | 0.35 | −0.60 ± 0.48 | −1.79 ± 0.75 | 2.28 | 0.0007 | 0.0157 |
miR-130b-3p | −4.16 ± 0.48 | −4.16 ± 0.22 | Undetected | −4.16 ± 0.38 | −4.84 ± 0.32 | 1.60 | 0.0017 | 0.0287 |
miR-192-5p | −2.18 ± 0.55 | −2.21 ± 0.86 | −2.19 | −2.20 ± 0.62 | −3.14 ± 0.38 | 1.92 | 0.0017 | 0.0287 |
miR-25-3p | 1.25 ± 0.56 | 1.09 ± 0.16 | 0.79 | 1.14 ± 0.41 | 0.44 ± 0.49 | 1.63 | 0.0027 | 0.0389 |
miR-215-5p | −3.18 ± 0.74 | −3.58 ± 0.57 | −3.51 | −3.35 ± 0.63 | −4.50 ± 0.64 | 2.21 | 0.0029 | 0.0389 |
miR-222-3p | −0.43 ± 0.44 | −0.09 ± 0.30 | 0.92 | −0.16 ± 0.56 | −1.27 ± 0.74 | 2.16 | 0.0031 | 0.0389 |