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Table 3 The influence of hormones on hEDS symptoms (hEDS symptoms: chronic pain, fatigue)

From: Gynecologic symptoms and the influence on reproductive life in 386 women with hypermobility type ehlers-danlos syndrome: a cohort study

  hEDS patients not influenced by menstruation
n = 197 (%)
hEDS patients influenced by menstruation
n = 133 (%)
p
Influenced by puberty 85/197 (43.2) 79/133 (58.7) 0.01
Impact of CHC    
Worsened on CHC 5/90 (5.6) 15/58 (25.9) 0.001
Improved on CHC 12/90 (13.3) 9/58 (15.5)
Unchanged on CHC 73/90 (81.1) 34/58 (58.6)
Improved by menopause 6/33 (18.2) 3/17 (17.7) NS