Table 1 General characteristics of the hEDS population (n = 386)

Age at inclusion [mean (SD); in years]

37.8 (14.1)

Age at diagnosis [mean (SD); in years]

35.3 (14.2)

Age at first symptoms [mean (SD); in years]

12.5 (11.8)

Age at puberty [mean (SD); in years]

12.5 (1.7)

hEDS symptoms

 Joint pain (%)

370 (96)

 Fatigue (%)

353 (92)

 Luxation (%)

333 (86)

Digestive disorders (%)

345 (90.1)

Migraine and headache (%)

289 (75.5)