Skip to main content

Table 4 Comparison of HRQoL according to the EQ-5D utility value in MPS IVA (Morquio A) patients with different levels of mobility impairment and other serious chronic diseases

From: Health-related quality of life in mucopolysaccharidosis: looking beyond biomedical issues

Disease

HRQoL mean utilitya

MPS IVA: adults, no wheelchair [28]

0.846

MPS IVA: adults, sometimes wheelchair [28]

0.582

MPS IVA: adults, always wheelchair [28]

0.057

Multiple sclerosis, walking-aid [75]

0.460

Multiple sclerosis, bedridden [75]

−0.195

Moderate to severe rheumatoid arthritis [76]

0.489

Chronic ischaemic heart disease [77]

0.640

Non-insulin dependent diabetes mellitus [77]

0.670

  1. aEQ-5D utility scores were calculated using a time tradeoff method [78]. This generates scores ranging from −0.59 to 1, where 1 means full health and zero stands for death. Negative scores could be emotively interpreted as a health state “worse than death”. Tradeoff tariffs used differed depending on the ethnic background of patients