Table 2 Clinical response to two years of letrozole treatment of McCune–Albright syndrome patients with precocious puberty
At start of letrozole treatment | Two years after letrozole treatment | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Patient | Sex | CA (years) | Height (cm) (SDS) | BA-CA (months) | Vaginal bleeding | Tanner stage | Height (cm) (SDS) | BA-CA (months) | Vaginal bleeding | Tanner stage |
7 | F | 3.3 | 96.9 (−0.4) | 8 | + | IIIB | 110 (−0.5) | 4 | - | IIB |
8 | F | 6.7 | 132.4 (1.9) | 26 | + | IIIB | 144.4 (1.9) | 29 | - | IIIB |
9 | F | 6.7 | 135.6 (2.4) | 6 | + | IVB | 146.3 (2.2) | 31 | + | IVB |
10 | F | 2.2 | 86.7 (−1.7) | 4 | + | IIIB | 93.9 (−1.8) | 26 | + | IIB |
11 | F | 8.1 | 134.5 (1.4) | 11 | + | IIIB | 143.4 (0.8) | 15 | + | IIIB |