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Table 3 Skeletal muscle properties of patients with mitochondrial myopathy (n = 6) and healthy controls (n = 8)

From: Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopathy

  Patients Controls P-value
Type I fibers (%) 34.8 ± 3.6 55.7 ± 5.9 < 0.001
Type II fibers (%) 65.2 ± 3.6 44.3 ± 5.9 < 0.001
CSA total (μm2) 3,438 ± 915 4,698 ± 1,328 0.070
CSA type I fibers (μm2) 3991 ± 1211 5234 ± 1566 0.133
CSA type II fibers (μm2) 3,178 ± 852 4,359 ± 1,592 0.127
MitoVD (%) 4.0 ± 0.5 5.1 ± 0.8 < 0.05
IMFVD (%) 3.4 ± 0.4 4.1 ± 0.5 < 0.05
SSVD (%) 0.6 ± 0.3 1.0 ± 0.5 0.118
LDVD (%) 0.4 ± 0.1 0.4 ± 0.3 0.660
  1. Values are represented as means ± SD. CSA cross sectional area; IMF VD intermyofibrilar mitochondrial volume density, LD VD lipid droplet volume density, Mito VD mitochondrial volume density, SS VD subsarcolemmal mitochondrial volume density