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Table 1 Physiological characteristics of patients with mitochondrial myopathy (n = 6) and healthy controls (n = 8)

From: Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopathy

  Patients Controls P-value
Age (yr) 53 ± 9 58 ± 14 0.437
Body mass (kg) 75 ± 18 67 ± 12 0.376
Height (cm) 162 ± 7 167 ± 7 0.238
BMC (kg) 2.3 ± 0.18 2.4 ± 0.4 0.867
Fat mass (kg) 23.1 ± 16.3 14.2 ± 11.6 0.255
Lean mass (kg) 38.4 ± 13.3 41.4 ± 13.9 0.683
Lean mass legs (kg) 19.3 ± 11.1 19.0 ± 8.8 0.951
Total body fat (%) 39 ± 13 31 ± 6 0.153
Relative O2peak (mL min−1 kg−1) 19.8 ± 6.8a 32.6 ± 7.3 <0.01
P peak (W) 78 ± 21a 165 ± 60 < 0.05
[L]rest (mmol L−1) 1.64 ± 0.88 1.11 ± 0.62 0.207
RER25W (-) 0.72 ± 0.06a 0.69 ± 0.06 0.447
RERrel (-) 0.78 ± 0.08a 0.77 ± 0.05 0.923
HRpeak(min−1) 144 ± 28a 158 ± 16 0.257
tlim (s) 278 ± 154a 541 ± 321 0.118
MVC (Nm) 54.3 ± 41.9a 80.6 ± 43.3b 0.278
  1. Values are represented as means ± SD. BMC bone mineral content; [L], blood lactate concentration at rest; HR peak peak heart rate, MVC maximum voluntary contraction, P peak peak power; relative O2peak, peak oxygen uptake per kg body weight; RER 25W respiratory exchange ratio at 25 W, RER rel respiratory exchange ratio at 50 % P peak, t lim time to exhaustion. a n = 5; b n = 7