Table 2 Comparison of clinical features in patients with Joubert syndrome vs. those with inconclusive MRI findings
From: Nosological delineation of congenital ocular motor apraxia type Cogan: an observational study
Neuroradiological diagnosis | Joubert syndrome | Inconclusive MRI | T | p |
|---|---|---|---|---|
Number of patients | 11 | 8 | ||
Sex | 8 male, 3 female | 3 male, 5 female | ||
Present age (years) [mean (SD)] | 12.0 (8.3) | 10.4 (6.4) | 0.46 | 0.65 |
Age at diagnosis of COMA (months) [mean (SD)] | 6.2 (2.7) | 5.4 (2.4) | 0.67 | 0.51 |
Amelioration of OMA | 100 % (11/11) | 100 % (8/8) | ||
Unsupported walking at age (months) [mean (SD)] | 28.0 (7.7) | 22.5 (4.3) | 1.82 | 0.09 |
Cognitive development: | Fisher´s exact test: p = 0.055 | |||
Normal | 3 | 6 | ||
Learning disability or intellectual disability | 8 | 2 | ||