Table 4 Hypothalamic and autonomic features present in ROHHAD patients

Hypothalamic Dysfunction

 Hyperprolactinemia

4

 Hypothyroidism

4

 Hypernatremia

3

 Polydipsia

2

 Hyperphagia

3

 Growth Hormone Deficiency

2

 Adipsia

1

 Adrenal Insufficiency

1

 Diabetes Insipidus

1

Autonomic Dysregulation

 Bradycardia

3

 Thermal Dysregulation

3

 Gastrointestinal Dysmotility

2

 Hypotension

2

 Tumor of neural crest origin

1