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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Common disease signatures from gene expression analysis in Huntington’s disease human blood and brain

Fig. 2

Significantly correlated blood modules with 4 different disease phenotypes. Each module was assigned a different color name, cf standard WGCNA. Significant modules were identified by correlating the module eigengenes (first principle component of the summary of gene expression profiles within a module) to the disease phenotypes, i.e. carrier status, CAG repeat, motor score and Total Functional Capacity (TFC) score, a measure for disease severity. On the y-axis: the top 8 correlated modules, x-axis: the disease phenotypes. The numbers represent the P v a l u e for the correlation per module. Green: negative correlation, red: positive correlation. The intensity of the color depicts the strength of the correlation

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