Table 2 Top 20 symptoms

1

Asthenia, general weakness, increased fatigue

180

36.6 %

69

33.5 %

111

38.8 %

0.2271

2

Arthralgia

124

25.2 %

50

24.3 %

74

25.9 %

0.6863

3

Abdominal discomfort and pain

113

23.0 %

37

18.0 %

76

26.6 %

0.0251

4

Headache

91

18.5 %

25

12.1 %

66

23.1 %

0.0020

5

Back pain

84

17.1 %

26

12.6 %

58

20.3 %

0.0259

6

Full body pain

82

16.7 %

31

15.0 %

51

17.8 %

0.4137

7

Dizziness

81

16.5 %

30

14.6 %

51

17.8 %

0.3347

8

Localized pain in a single extremity

79

16.1 %

36

17.5 %

43

15.0 %

0.4669

9

Generalized myalgia

76

15.4 %

30

14.6 %

46

16.1 %

0.6452

10

Gait difficulties

73

14.8 %

33

16.0 %

40

14.0 %

0.5313

11

Paresthesia and dysesthesia

61

12.4 %

23

11.2 %

38

13.3 %

0.4811

12

Muscle cramps and spasms

59

12.0 %

21

10.2 %

38

13.3 %

0.2975

13

Nausea and vomiting

55

11.2 %

12

5.8 %

43

15.0 %

0.0014

14

Palpitations, heart rhythm abnormalities

54

11.0 %

21

10.2 %

33

11.5 %

0.6379

15

Visual disorder, disturbance or defects

53

10.8 %

25

12.1 %

28

9.8 %

0.4077

16

Abnormal stool consistency and frequencies

51

10.4 %

17

8.3 %

34

11.9 %

0.1918

17

Dyspnea

43

8.7 %

16

7.8 %

27

9.4 %

0.5167

18

Dyssomnia

39

7.9 %

16

7.8 %

23

8.0 %

0.9113

Sensation of abnormal heat or cold

39

7.9 %

18

8.7 %

21

7.3 %

0.5720

19

Edema

37

7.5 %

8

3.9 %

29

10.1 %

0.0094

20

Hyperhidrosis

34

6.9 %

14

6.8 %

20

7.0 %

0.9323

Exanthema, erythema

34

6.9 %

13

6.3 %

21

7.3 %

0.6561