From: Characteristics of patients contacting a center for undiagnosed and rare diseases
Total (n = 413) | Men (n = 171) | Women (n = 242) | |||||||
---|---|---|---|---|---|---|---|---|---|
Rank | ICD | ICD Caption | (n) | (%) | (n) | (%) | (n) | (%) | χ 2 p-value |
1 | M79 | Other soft tissue disorders, not elsewhere classified (incl. fibromyalgia, myalgia, neuralgia, rheumatism) | 63 | 15.3 % | 16 | 9.4 % | 47 | 19.4 % | 0.0051 |
2 | F45 | Somatoform disorders | 51 | 12.3 % | 18 | 10.5 % | 33 | 13.6 % | 0.3440 |
3 | G62 | Other polyneuropathies (incl. alcoholic, drug induced, toxic, unspecified polyneuropathies) | 36 | 8.7 % | 17 | 9.9 % | 19 | 7.9 % | 0.4582 |
4 | M54 | Dorsalgia | 30 | 7.3 % | 9 | 5.3 % | 21 | 8.7 % | 0.1879 |
5 | I10 | Essential (primary) hypertension | 29 | 7.0 % | 15 | 8.8 % | 14 | 5.8 % | 0.2420 |
6 | F32 | Depressive episode | 28 | 6.8 % | 11 | 6.4 % | 17 | 7.0 % | 0.8136 |
M35 | Other systemic involvement of connective tissue (incl. sicca syndrome, overlap syndrome, polymyalgia rheumatica) | 28 | 6.8 % | 5 | 2.9 % | 23 | 9.5 % | 0.0088 | |
A69 | Other spirochetal infections (incl. Lyme’s disease) | 28 | 6.8 % | 16 | 9.4 % | 12 | 5.0 % | 0.0799 | |
7 | K58 | Irritable bowel syndrome | 25 | 6.1 % | 12 | 7.0 % | 13 | 5.4 % | 0.4897 |
8 | T78 | Adverse effects, not elsewhere classified (incl. food allergies) | 24 | 5.8 % | 8 | 4.7 % | 16 | 6.6 % | 0.4082 |
9 | G93 | Other disorders of brain (incl. postviral fatigue syndrome) | 21 | 5.1 % | 10 | 5.8 % | 11 | 4.5 % | 0.5529 |
10 | K29 | Gastritis and duodenitis | 20 | 4.8 % | 5 | 2.9 % | 15 | 6.2 % | 0.1268 |
11 | M19 | Other arthrosis | 19 | 4.6 % | 6 | 3.5 % | 13 | 5.4 % | 0.3733 |
12 | M47 | Spondylosis | 18 | 4.4 % | 4 | 2.3 % | 14 | 5.8 % | 0.0911 |
13 | G47 | Sleep disorders (incl. sleep apnea) | 17 | 4.1 % | 13 | 7.6 % | 4 | 1.7 % | 0.0027 |
14 | E03 | Other hypothyroidism | 16 | 3.9 % | 7 | 4.1 % | 9 | 3.7 % | 0.8460 |
G25 | Other extrapyramidal and movement disorders (incl. restless legs syndrome) | 16 | 3.9 % | 10 | 5.8 % | 6 | 2.5 % | 0.0806 | |
M51 | Other intervertebral disc disorders | 16 | 3.9 % | 6 | 3.5 % | 10 | 4.1 % | 0.7464 | |
15 | E55 | Vitamin D deficiency | 14 | 3.4 % | 7 | 4.1 % | 7 | 2.9 % | 0.5065 |