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Table 2 Displayed are the detection rates (Pi*ZZ) of different time periods, the characteristics of the population screened at that time (age in years; mean ± standard deviation) and the three most frequent clinical characteristics that led to the test initiation. Numbers do not add up to 18,683, because for some individuals the gender was not recorded and could not be deducted by the name

From: Results from a large targeted screening program for alpha-1-antitrypsin deficiency: 2003 - 2015

 

Detection rate [%]

Age [years]

Male/female

Most frequent clinical characteristics

2003/04/05

8.65

39.8 ± 21.9

1105/887

1. Cough

2. Emphysema

3. Wheezing

2006/07

4.04

40.4 ± 21.7

1527/1399

1. Dyspnoea on exertion

2. Cough

3. Wheezing

2008/09

4.25

48.9 ± 21.6

1973/1791

1. Dyspnoea on exertion

2. Cough

3. Phlegm

2010/11

4.98

48.2 ± 20.3

2127/1888

1. Dyspnoea on exertion

2. Cough

3. Phlegm

2012/13

7.91

47.9 ± 19.1

1808/1661

1. Dyspnoea on exertion

2. Cough

3. COPD

2014/15

11.26

48.5 ± 18.8

1280/1139

1. Dyspnoea on exertion

2. COPD

3. Cough

All

6.85

45.9 ± 20.8

9820/8765

1. Dyspnoea on exertion

2. Cough

3. COPD