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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Pulmonary and pleural lymphatic endothelial cells from pediatric, but not adult, patients with Gorham-Stout disease and generalized lymphatic anomaly, show a high proliferation rate

Fig. 2

Lymphatic proliferation rate in patients with Gorham-Stout disease (GSD) and generalized lymphatic anomaly (GLA). a Quantification of lymphatic vessels with actively proliferating lymphatic endothelial cells in lung and pleural tissue. Statistical analysis was performed using Mann-Whitney rank sum test. Horizontal lines indicate median value. Open symbols: children (6 months-16 years of age). Black symbols: adults (>23 years of age). b-e Immunohistochemical staining for Ki67 (brown-colored nuclei) and D2-40 (in green) in patients with GSD/GLA. Representative photomicrographs of histological sections of lung tissue (b-c) and pleural tissue (d-e). Cell nuclei were counterstained with Mayer’s hematoxylin (blue). Scale bars: (b-e) 50 μm

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172