A longitudinal investigation into cognition and disease progression in spinocerebellar ataxia types 1, 2, 3, 6, and 7

Table 3 Impairment on neuropsychological assessments in each group

	SCA 1 (n = 2)		SCA2 (n = 2)		SCA3 (n = 2)		SCA6 (n = 4)		SCA7 (n = 3)
	Baseline	Follow-up	Baseline	Follow-up	Baseline	Follow-up	Baseline	Follow-up	Baseline	Follow-up
Executive Function
Verbal Fluency FAS (<10th%ile)	0	1	0	0	1	2	0	0	1	1
Hayling Test (scaled score <3)	0	0	1	1	1	1	2	2	2	1
Stroop C-W Test (<5th%ile)	0	2	0	1	1	1	0	1	2^a	1^a
Speed and Attention
Oral Symbol Digit Modalities Test (<5th%ile)	0	2	1	1	1	2	1^a	1^a	2	2
Elevator Counting with Distraction (<5th%ile)	1	1	1	1	1	0	0	0	0	0
Elevator Counting (score <5)	0	0	0	0	0	1	0	0	0	0
Recognition Memory
RMW (<5th%ile)	0	1	0	1	0	0	0	0	0	0
RMF (<5th%ile)	0	2	0	0	1	2	0	0	1	2

Values displayed are number of patients that were impaired on each task, with specific thresholds in brackets (based on normalised scores). RMW/RMF = Recognition Memory Test, Words/Faces. ^ameans some data missing

ISSN: 1750-1172