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Table 2 Expression of genes near the chromosome 14 and 18 breakpoints

From: Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability

Chromosome 18
Gene Chromosome UDP4637 FPKM Control FPKM log (UDP/Control) p-value q-value Significant
MBD2 chr18 10.0 9.0 −0.15 0.250 0.39 no
SNORA37 chr18 0.0 0.0 0.00 1.000 1.00 no
POLI chr18 3.7 2.7 −0.47 0.001 0.00 yes a
STARD6 chr18 0.0 0.0 0.00 1.000 1.00 no
C18orf54 chr18 3.0 1.4 −1.09 0.000 0.00 yes a
DYNAP chr18 2.6 0.0 N/A 0.000 0.00 yes a
RAB27B chr18 0.6 1.7 1.52 0.000 0.00 yes a
CCDC68 chr18 0.3 1.1 2.02 0.000 0.00 yes a
TCF4 chr18 17.6 21.5 0.29 0.026 0.06 no
LOC100505474 chr18 0.0 0.0 0.00 1.000 1.00 no
TXNL1 chr18 22.5 25.7 0.19 0.155 0.27 no
WDR7 chr18 6.7 6.4 −0.08 0.563 0.70 no
BOD1P chr18 0.0 0.0 inf 1.000 1.00 no
Chromosome 14
Gene Chromosome UDP4637 FPKM Control FPKM log (UDP/Control) p-value q-value Significant
TEX21P chr14 0.1 0.1 −0.04 1.00 1.00 no
MTHFD1 chr14 32.0 29.4 −0.12 0.36 0.51 no
AKAP5 chr14 0.1 0.5 2.15 0.00 0.00 yes a
ZBTB25 chr14 2.4 2.5 0.08 0.66 0.78 no
ZBTB1 chr14 13.2 14.6 0.15 0.28 0.42 no
HSPA2 chr14 53.3 120.4 1.18 0.00 0.00 yes
PPP1R36 chr14 0.3 0.3 0.16 0.71 0.81 no
PLEKHG3 chr14 2.5 3.2 0.35 0.02 0.05 yes a
SPTB chr14 0.0 0.1 0.74 1.00 1.00 no
CHURC1,CHURC1-FNTB,FNTB chr14 20.3 20.4 0.01 0.97 0.98 no
GPX2 chr14 0.0 0.0 inf 1.00 1.00 no
LOC100506321 chr14 0.0 0.1 1.83 1.00 1.00 no
MAX chr14 23.2 18.8 −0.31 0.26 0.40 no
MIR4706 chr14 0.0 0.0 0.00 1.00 1.00 no
RAB15 chr14 3.4 2.3 −0.54 0.23 0.37 no
  1. a FPKM value too low to interpret as significant (as evaluated by cufflinks)