TY - JOUR AU - Ju, Jun AU - Hirose, Shinichi AU - Shi, Xiu-Yu AU - Ishii, Atsushi AU - Hu, Lin-Yan AU - Zou, Li-Ping PY - 2016 DA - 2016/05/04 TI - Treatment with Oral ATP decreases alternating hemiplegia of childhood with de novo ATP1A3 Mutation JO - Orphanet Journal of Rare Diseases SP - 55 VL - 11 IS - 1 AB - Alternating hemiplegia of childhood is an intractable neurological disorder characterized by recurrent episodes of alternating hemiplegia accompanied by other paroxysmal symptoms. Recent research has identified mutations in the ATP1A3 gene as the underlying cause. Adenosine-5'-triphosphate has a vasodilatory effect, can enhance muscle strength and physical performance, and was hypothesized to improve the symptoms of paroxysmal hemiplegia. SN - 1750-1172 UR - https://doi.org/10.1186/s13023-016-0438-7 DO - 10.1186/s13023-016-0438-7 ID - Ju2016 ER -