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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Alternative laronidase dose regimen for patients with mucopolysaccharidosis I: a multinational, retrospective, chart review case series

Fig. 2

Changes in cardiac valve disease over time for patients with severe (Hurler, panel A) or attenuated MPS I (Hurler-Scheie, panel B and Scheie, panel C). Cardiac symptoms improved in Patients 1, 11, 14 and 20 at T2 or T3. Signs at T1 remained stable at T2 and T3 in Patients 4, 6, 10, 12, 15, 16, 17, and 18. Signs progressed in Patients 2, 3, 5, 13 and 17. Signs at T3 were absent or mild in Patients 1, 4, 10-14, and 16-20

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