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Table 1 Demographics and baseline characteristics of the studied subjects

From: MUC1 gene polymorphisms are associated with serum KL-6 levels and pulmonary dysfunction in pulmonary alveolar proteinosis

Variables PAP Controls p value
n = 24 n = 30
Demographics    
 Age, years 46 ± 2 41 ± 2 n.s.
 Gender, male/female, n 14/10 11/19 n.s.b
 Smoking history, Current/Non, n 9/15 4/26 0.06b
 BMI (kg/m2) 26 ± 1 24 ± 1 n.s.
Pulmonary function    
 FVC (% pred) 80 ± 4 97 ± 7 <0.0001
 FEV1 (% pred) 74 ± 3 93 ± 2 <0.0001
 PaO2 (mmHg) 69 ± 3 84 ± 1 0.005
 TLC (% pred) 81 ± 3 94 ± 3 0.025
 SaO2 (%) 94 ± 1 95 ± 1 n.s.
 A-aDO2 (mmHg) 40 ± 3 8 ± 1 <0.0001
 DLco (% pred) 50 ± 21 86 ± 10 0.002
Biomarkers    
 GM-CSF autoantibody (μg/mL)a 52 ± 6 4 ± 1 <0.0001
 KL-6 (U/mL)a 5004 ± 983 283 ± 19 0.0001
 LDH (IU/L)a 312 ± 24 193 ± 6 <0.0001
  1. Unless otherwise indicated, values are expressed as mean ± SE.
  2. n.s. not significant
  3. aThe cut-off of normality for each biomarker is reported in the methods
  4. bFischer’s exact test, all other comparisons with student’s t-test