Table 1 Demographics and baseline characteristics of the studied subjects

Demographics

 Age, years

46 ± 2

41 ± 2

n.s.

 Gender, male/female, n

14/10

11/19

n.s.^b

 Smoking history, Current/Non, n

9/15

4/26

0.06^b

 BMI (kg/m²)

26 ± 1

24 ± 1

n.s.

Pulmonary function

 FVC (% pred)

80 ± 4

97 ± 7

<0.0001

 FEV₁ (% pred)

74 ± 3

93 ± 2

<0.0001

 PaO₂ (mmHg)

69 ± 3

84 ± 1

0.005

 TLC (% pred)

81 ± 3

94 ± 3

0.025

 SaO₂ (%)

94 ± 1

95 ± 1

n.s.

 A-aDO₂ (mmHg)

40 ± 3

8 ± 1

<0.0001

 DLco (% pred)

50 ± 21

86 ± 10

0.002

Biomarkers

 GM-CSF autoantibody (μg/mL)^a

52 ± 6

4 ± 1

<0.0001

 KL-6 (U/mL)^a

5004 ± 983

283 ± 19

0.0001

 LDH (IU/L)^a

312 ± 24

193 ± 6

<0.0001