Table 3 Cost of illness (COI) per patient for SMA [in €/y]
Mean | Ratio of total COI [%] | SMA subtype | |||
|---|---|---|---|---|---|
I | II | III | |||
Outpatient medical costs | 331 (579) | 0 % | 463 (455) | 392 (496) | 274 (640) |
Inpatient medical costs | 5,634 (24,193) | 8 % | 39,972 (81,057) | 4,454 (11,892) | 2,488 (10,730) |
Rehabilitation costs (in-/outpatient) | 822 (3,535) | 1 % | 594 (2,059) | 971 (3,901) | 745 (3,423) |
Drug treatment costs | 189 (527) | 0 % | 389 (1,232) | 245 (563) | 126 (334) |
Costs for use of rehabilitation services | 2,050 (2,094) | 3 % | 3,488 (4,734) | 2,149 (1,641) | 1,814 (1,849) |
Costs for artificial nutrition | 243 (1,157) | 0 % | 1,940 (3,351) | 247 (1,139) | 90 (573) |
Costs for medical aids | 3,451 (2,450) | 5 % | 1,648 (1,628) | 4,385 (2,133) | 3,003 (2,508) |
Costs for respiratory management | 1,678 (2,760) | 2 % | 5,698 (5,882) | 2,548 (2,280) | 594 (1,713) |
Total direct medical COI | 14,342 (26,379) | 20 % | 53,707 (81,809) | 15,305 (14,220) | 9,125 (14,330) |
Costs for housing | 12,854 (38,639) | 18 % | 10,160 (26,569) | 20,001 (50,000) | 8,173 (29,107) |
Costs for personal assistance for school and work attendance | 2,162 (6,694) | 3 % | 0 | 4,301 (9,513) | 958 (3,794) |
Travel expenses | 2,800 (6,637) | 4 % | 2,068 (1,866) | 2,040 (2,525) | 3,424 (8,661) |
Informal care costs | 20,170 (28,924) | 29 % | 31,542 (22,541) | 28,571 (35,107) | 12,902 (22,173) |
Costs for legal advice | 9 (37) | 0 % | 0 | 12 (37) | 8 (39) |
Costs for constructional modifications to house | 1,860 (3,408) | 3 % | 833 (2,887) | 2,882 (4,511) | 1,254 (2,133) |
Costs for constructional modifications to automobile | 1,116 (2,577) | 2 % | 1,455 (4,824) | 1,751 (3,252) | 601 (1,193) |
Other expenditures | 129 (782) | 0 % | 20 (69) | 110 (847) | 156 (783) |
Total direct non-medical COI | 40,378 (47,464) | 58 % | 45,957 (39,044) | 58,607 (54,214) | 26,940 (38,381) |
Total direct COI | 54,721 (59,210) | 78 % | 99,664 (104,071) | 73,911 (60,597) | 36,064 (42,753) |
Indirect cost patients | 20,275 (22,857) | 29 % | 0 | 17,016 (18,782) | 20,906 (23,645) |
Indirect cost parents | 13,204 (17,264) | 19 % | 13,959 (11,582) | 19,034 (19,891) | 4,195 (9,637) |
Total indirect COI | 15,845 (20,067) | 22 % | 8,143 (11,173) | 16,356 (18,971) | 16,376 (21,511) |
Total COI | 70,566 (62,725) | 100 % | 107,807 (102,082) | 90,267 (65,467) | 52,440 (48,000) |