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Table 1 Metabolic control of PKU females during pregnancy, comparing dried blood Phe concentrations in planned and unplanned pregnancies (Mann-Whitney U-test)

From: Ten years of specialized adult care for phenylketonuria – a single-centre experience

Metabolic control during pregnancy

planned n = 16

unplanned n = 9

P

Median (range) number of laboratory controls

36 (17–47)

17 (1–30)

<0.001

Median (range) dried blood Phe concentration μmol/l

181 (101–485)

476 (172–878)

<0.001

Offspring with clinical signs of maternal PKU syndrome

0

3