Table 2 Genes included in the targeted next generation sequencing strategy
From: Uncommon nucleotide excision repair phenotypes revealed by targeted high-throughput sequencing
Official gene symbol | Legacy name | Ref Seq NM # | # Exons | Size of coding exons (bp) | Targeted region size (bp) | Theoretical coverage |
|---|---|---|---|---|---|---|
DDB1 | Â | NM_001923.4 | 27 | 3423 | 6,150 | 94.67Â % |
DDB2 | XPE | NM_000107.2 | 10 | 1284 | 2,268 | 99.03Â % |
ERCC1 | Â | NM_001983.3 | 10 | 894 | 2,102 | 99.57Â % |
ERCC2 | XPD | NM_000400.3 | 23 | 2283 | 4,894 | 98.12Â % |
ERCC3 | XPB | NM_000122.1 | 15 | 2349 | 3,864 | 99.48Â % |
ERCC4 | XPF | NM_005236.2 | 11 | 2751 | 3,862 | 100.00Â % |
ERCC5 | XPG | NM_000123.3 | 15 | 3561 | 5,076 | 100.00Â % |
ERCC6 | CSB | NM_000124.3 | 21 | 4482 | 9,127 | 99.99Â % |
ERCC8 | CSA | NM_000082.3 | 12 | 1191 | 3,256 | 98.65Â % |
GTF2H5 | TTD-A | NM_207118.2 | 3 | 216 | 418 | 100.00Â % |
MPLKIP | TTDN1 | NM_138701.3 | 2 | 540 | 742 | 100.00Â % |
POLH | Â | NM_006502.2 | 11 | 2142 | 3,152 | 100.00Â % |
USP7 | Â | NM_003470.2 | 31 | 3309 | 6,440 | 93.88Â % |
UVSSA | KIAA1530 | NM_020894.2 | 14 | 2130 | 3,443 | 99.07Â % |
XPA | Â | NM_000380.3 | 6 | 822 | 1,428 | 100.00Â % |
XPC | Â | NM_004628.4 | 16 | 2823 | 4,767 | 100.00Â % |
| Â | Â | Total | 227 | 34200 | 58,721 | Â |