Fig. 3From: Carglumic acid enhances rapid ammonia detoxification in classical organic acidurias with a favourable risk-benefit profile: a retrospective observational studyAmmonia profile in response to carglumic acid treatment. Endpoint NH3 in response to treatment with Carbaglu® for each of the diagnostic groups was 52.5 μmol/L (IVA), 67.7 μmol/L (MMA) and 47.8 μmol/L (PA). The time to achieve endpoint was equivalent for the three groups. IVA, isovaleric aciduria; MMA, methylmalonic aciduria; PA, propionic aciduria. Analysis by episode for the total efficacy population and for diagnosis subpopulationsBack to article page