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Table 4 Bronchodilator response in patients vs. controls

From: Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency

Bronchodilator responsea    
  Mean % change (SD)   P value (T-test)
Spirometry Patients n = 4 Controls n = 82  
 ΔFEV1 3.3 (4.7) 5.5 (9.7) 0.607
 ΔFVC 1.3 (6.5) 2.7 (7.0) 0.341
 ΔFEV1 / FVC 2.5 (4.6) 4.3 (8.1) 0.672
 ΔPEF −4.5 (13.7) 6.5 (15.5) 0.164
Impulse oscillometry Patients n = 10 Controls n = 82  
 ΔR5 −15.3 (15.9) −14.6 (12.0) 0.438
 ΔR10 −15.4 (12.5) −14.5 (10.7) 0.809
 ΔR20 −12.6 (11.1) −9.6 (12.7) 0.483
 ΔR5-R20 −8.5 (28.7) −11.7 (29.8) 0.745
 ΔX5 −18.2 (31.9) −14.7 (24.0) 0.673
 ΔAX −21.6 (29.7) −33.3(22.6) 0.139
 ΔFres −13.4 (15.8) −13.1 (20.9) 0.961
  1. aAirway reversibility was considered evident when there was an improvement in any of the following bronchodilator parameters : ΔR5 ≥ −20 %, ΔR10 ≥ −15 %, ΔR20 ≥ −20 %, ΔAX ≥ −45 %, and ΔFres ≥ −25 %. By design, the percent improvement (reversibility) is displayed as a negative number because it indicates a magnitude decrease in resistance or reactance