|
Bronchodilator responsea
| | | |
|---|
| |
Mean % change (SD)
| |
P value (T-test)
|
|---|
|
Spirometry
|
Patients n = 4
|
Controls n = 82
| |
|
ΔFEV1
|
3.3 (4.7)
|
5.5 (9.7)
|
0.607
|
|
ΔFVC
|
1.3 (6.5)
|
2.7 (7.0)
|
0.341
|
|
ΔFEV1 / FVC
|
2.5 (4.6)
|
4.3 (8.1)
|
0.672
|
|
ΔPEF
|
−4.5 (13.7)
|
6.5 (15.5)
|
0.164
|
|
Impulse oscillometry
|
Patients n = 10
|
Controls n = 82
| |
|
ΔR5
|
−15.3 (15.9)
|
−14.6 (12.0)
|
0.438
|
|
ΔR10
|
−15.4 (12.5)
|
−14.5 (10.7)
|
0.809
|
|
ΔR20
|
−12.6 (11.1)
|
−9.6 (12.7)
|
0.483
|
|
ΔR5-R20
|
−8.5 (28.7)
|
−11.7 (29.8)
|
0.745
|
|
ΔX5
|
−18.2 (31.9)
|
−14.7 (24.0)
|
0.673
|
|
ΔAX
|
−21.6 (29.7)
|
−33.3(22.6)
|
0.139
|
|
ΔFres
|
−13.4 (15.8)
|
−13.1 (20.9)
|
0.961
|
-
aAirway reversibility was considered evident when there was an improvement in any of the following bronchodilator parameters : ΔR5 ≥ −20 %, ΔR10 ≥ −15 %, ΔR20 ≥ −20 %, ΔAX ≥ −45 %, and ΔFres ≥ −25 %. By design, the percent improvement (reversibility) is displayed as a negative number because it indicates a magnitude decrease in resistance or reactance
