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Table 1 Distribution of genotypes obtained from E430025E21Rik wt/ko x E430025E21Rik wt/ko matings

From: The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8

 

Genotype

 

Age

wt/wt

wt/ko

ko/ko

p-value

P1

12

25

0

2.4 x 10−5

E19.5

2

3

0

0.23

E16.5

3

8

0

0.042

E13.5

4

6

0

0.056

Total

21

42

0

1.3 x 10−8

Ratio

1

2

0

 
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172