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Table 1 Percentage of vacuolation and CI of deep regions of cerebrum

From: The effects of intracisternal enzyme replacement versus sham treatment on central neuropathology in preclinical canine fucosidosis

Region

CVT (n = 3)

AET (n = 3)

AVT (n = 3)

CI

Corpus callosum

0.55 ± 0.1 a

5.78 ± 1.1 b

6.66 ± 1.4 b

0.13

Striatum

0.31 ± 0.1 a

2.65 ± 1.0 b

3.52 ± 1.3 b

0.25

Thalamus

0.34 ± 0.1 a

3.07 ± 0.9 b

4.03 ± 1.3 b

0.23

Medulla

0.78 ± 0.25 a

7.65 ± 2.4 b

7.68 ± 2.2 b

0.03

Spinal cord

4.63 ± 1.5 a

10.78 ± 3.5 b

12.79 ± 4.1 b

0.16

  1. Mean ± SEM. a,b different letters indicate significant difference between affected dogs and unaffected controls at p < 0.05