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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: The effects of intracisternal enzyme replacement versus sham treatment on central neuropathology in preclinical canine fucosidosis

Fig. 1

Quantification of neurodegenerative and inflammatory markers in frontal cerebral cortex following intracisternal enzyme infusion. Quantification of (a) area vacuolation in deep frontal cerebral cortex, (b) ‘vacuoles per neuron’ in deep frontal cerebral cortex, (c) vacuolation in superificial frontal cerebral cortex, (d) ‘vacuoles per neuron’ in deep frontal cerebral cortex, (e) average thickness of perivascular space in frontal cerebral cortex, (f) LFB/PAS staining in deep white matter tracts of frontal cerebral cortex following enzyme infusion, (g) area GFAP staining in frontal cerebral cortex, (h) area RCA-1 lectin staining in frontal cerebral cortex. Different letters (a, b, c) indicate significant difference between groups at p < 0.05

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