Fig. 3From: Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutationsMuscle and skin microscopy. a-d Fatty tissue, fragmented muscle fascicles next to normal fascicles in individuals F1 (a-b) or nonspecific myopathic changes with variation in fiber size in proband F2 (c-d) (Hematoxylin and eosin staining [H&E]; ×20 (a) and ×100 magnification (b-d)). e-f Epidermal atrophy, scleroderma-like features with a diffuse mild collagen sclerosis (e) (individual F1; H&E; ×20 magnification); elastic dystrophy with formation of elastic globes (arrowheads) in the papillary dermis (f) (individual F1; Weigert staining; ×150 magnification)Back to article page