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Table 1 Effect of genotype on VEP latency and amplitude in naive PN75 Npc1 +/+ and Npc1 −/− micea

From: Visual evoked potentials of Niemann-Pick type C1 mice reveal an impairment of the visual pathway that is rescued by 2-hydroxypropyl-ß-cyclodextrin

  Npc1 +/+ (n = 12) Npc1 −/− (n = 12) t (df) b p c
Latency, N1 27.59 ± 0.16d 28.98 ± 0.59 2.29 (22) 0.0396
Latency, N2 35.08 ± 0.62 37.35 ± 0.55 2.75 (22) 0.0118
Latency, N3 43.37 ± 0.81 44.70 ± 0.85 1.14 (22) 0.2778
Amplitude, N1 105.20 ± 13.67 22.00 ± 6.32 5.52 (22) 0.0001
  1. aThe mice examined in this experiment did not receive any kind of experimental manipulation before electrode implants and VEP recording
  2. bDegree of freedom
  3. c p was evaluated by unpaired two-tailed Student’s t test
  4. dmean ± SEM