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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Primary erythromelalgia: a review

Fig. 1

Schematic of voltage-gated sodium channel alpha subunit and localization of reported PE mutations. The alpha subunit consists of four domains (I-IV). Each domain contains six helical transmembrane segments (S1-S6). The S4 segment of each domain contains positively charged amino acid residues

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