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Table 2 Changes in left ventricular ejection fraction functional parameter, after approximately 10 years of agalsidase alfa treatment

From: Effectiveness of agalsidase alfa enzyme replacement in Fabry disease: cardiac outcomes after 10 years’ treatment

  Females Males
Left ventricular ejection fraction (%)
Baseline, mean (SD) 71.9 (7.6), n = 23 69.9 (7.3), n = 21
10-year n, mean (SD) 68.4 (6.9) 69.8 (7.0)
Change from baselinea −3.64 (−6.74, −0.54) 1.31 (−2.16, 4.78)
p = 0.022 p =0.4546
  1. aAdjusted changes from baseline: LS mean (95 % CI) changes
  2. CI: confidence interval; LS: least squares; SD: standard deviation