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Table 2 Changes in left ventricular ejection fraction functional parameter, after approximately 10 years of agalsidase alfa treatment

From: Effectiveness of agalsidase alfa enzyme replacement in Fabry disease: cardiac outcomes after 10 years’ treatment

 

Females

Males

Left ventricular ejection fraction (%)

Baseline, mean (SD)

71.9 (7.6), n = 23

69.9 (7.3), n = 21

10-year n, mean (SD)

68.4 (6.9)

69.8 (7.0)

Change from baselinea

−3.64 (−6.74, −0.54)

1.31 (−2.16, 4.78)

p = 0.022

p =0.4546

  1. aAdjusted changes from baseline: LS mean (95 % CI) changes
  2. CI: confidence interval; LS: least squares; SD: standard deviation