Table 1 Summary of parameters and statistics for bone mineral analysis by DEXA and tibia length by X-ray in the IDUA KO mice at the age of 16 weeks (mean ± SEM)
| Â | Parameters | Male | Female | ||
|---|---|---|---|---|---|
WT (n = 4) | KO (n = 4) | WT (n = 5) | KO (n = 6) | ||
Femur | BMD (g/cm2) | 0.064 ± 0.001 | 0.074 ± 0.002**** | 0.059 ± 0.002 | 0.068 ± 0.002*** |
BMC (g) | 0.031 ± 0.001 | 0.037 ± 0.0002* | 0.03 ± 0.0008 | 0.038 ± 0.001**** | |
Bone area (cm2) | 0.48 ± 0.007 | 0.505 ± 0.006**** | 0.502 ± 0.018 | 0.553 ± 0.006 | |
Body | BMD (g/cm2) | 0.047 ± 0.001 | 0.053 ± 0.0005** | 0.046 ± 0.0004 | 0.051 ± 0.0006* |
BMC (g) | 0.547 ± 0.032 | 0.755 ± 0.027** | 0.0541 ± 0.014 | 0.700 ± 0.017* | |
Bone area (cm2) | 11.703 ± 0.388 | 14.233 ± 0.503*** | 11.806 ± 0.348 | 13.787 ± 0.237* | |
|  | Tibia length (mm) | 18.043 ± 0.239 | 17.555 ± 0.147 | 18.396 ± 0.110 | 18.099 ± 0.105 |