Fig. 1
From: Ichthyosis with confetti: clinics, molecular genetics and management
Major clinical features of ichthyosis with confetti. Severe ichthyosiform erythroderma: massive verrucous hyperkeratosis on the buttocks (a), knees (b) and feet (c) in the absence of retinoid therapy. Confetti-like spots of healthy skin are visible on the trunk and cheek (d, e: black rings) of the same patient. Note the presence of mammillae hypoplasia (d, arrowheads). Ear malformations: hypoplasia of the ear helix (e, f), and lobule (e). Clinical pictures are from a 8-year-old male (a-e) and a 1-year-old female (f)