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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Friedreich ataxia in Norway – an epidemiological, molecular and clinical study

Fig. 3

Frataxin levels in whole blood in FRDA patients, carriers and controls. The frataxin level is significantly different between the three groups and correlates with number of GAA1 repeats in FRDA patients and healthy carriers. The levels of frataxin were measured in blood from FRDA patients (N = 26), healthy carriers (N = 37) and healthy controls (N = 27). a The Tukey box plot shows pg frataxin per μg (mcg) total protein. The whiskers extends to a maximum of 1.5 x interquartile range (IQR) beyond the edge of the box (“Tukey’s inner fence”). Values outside these fences represent outliers and are marked as dots. b Linear regression analyses were performed to analyze the correlation between frataxin levels (pg/mcg) in blood and number of GAA1 repeats in FRDA patients (upper plot), number of GAA2 repeats in healthy carriers (middle plot) and number of GAA2 repeats in healthy controls. R2 = coefficient of determination

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