Fig. 1

Standard scores for the Vineland II Communication, Living Skills, Social, and Motor domains. 50^th percentile in the general population is 100. Average Scores reflect mild to moderate impairments in adaptive skills in patients with PMS. Blue Bars represent the entire dataset, red bars represent the subgroup who we identified to carry SHANK3 Variants green bars represent the subgroup who were confirmed not to carry a SHANK3 Variant. Error Bars represent the Standard Error of the Mean